Personal Information

• Name: PROF. DR ISMAIL TAHA IBRAHIM
• Current address: Mansura, Egypt
• Mobile no: 00201002349504 whatsapp    009647710066284  whatsapp
• Mail: ismailtaha_73@yahoo.com - ismail@uoalhuda.edu.iq
• SEX: Male
• Date of birth: 05 /01 /1973
• NATIONALITY: Egyptian
• Marital Status: Married

Academic and Scientific Qualifications    

• Ph. D. in Pharmaceutical sciences (Pharmacology) Faculty of Pharmacy, Mansura University. (2008)
• M. Sc. in Pharmaceutical sciences (Pharmacology) Faculty of Pharmacy, Mansura University. (2005)
•B.Sc. Pharmacy Faculty of Pharmacy, Mansura University. (1996)
•CURRENT POSITION: Professor of pharmacology and toxicology, Head of Department of Pharmacy, Al-Huda University college Al Anbar, Iraq.

Preferred Research Areas

• Radiodiagnosis and radiotherapy studies e.g., radiolabeling of pharmaceutical compounds.
• Drug targeting.
• Development and characterization of new anticancer agents.
• Inflammation studies and diagnosis.
• Stability and bioavailability studies.
• Radiopharmaceutical development and quality control studies
• In vivo-vitro correlation studies.

Academic and Administrative Experience

• Lecture of pharmacology and toxicology
• Assistant Professor of Pharmacology, toxicology and radio pharmacy, Egyptian atomic energy authority, Cairo, Egypt.
• Associate Professor of Pharmacology and toxicology, Faculty of Pharmacy, Delta University, Egypt.
• Associate Professor of Pharmacology and toxicology Faculty of Pharmacy, Al-Bayan University, Iraq.
• Professor of Pharmacology and toxicology Faculty of Pharmacy, Al-Bayan University, Iraq.
• Professor of Pharmacology and toxicology Department of Pharmacy, Al-Huda University college Al Anbar, Iraq.

Teaching Courses

• Human biology
• Histology
• Physiology
• pathophysiology
• Pharmaceutical microbiology
• Pharmacology
• Toxicology
• Pharmacy Ethics
• Radio pharmacy
• Pharmacoeconomics

Activities and Workshops

Activities:
• Prof of pharmacology and Head of Pharmacy department Al-Huda University college.
• More than 70 research items
• Supervisors of more than 20 master and Ph. Degree in pharmacy field.
• Active participation in the activities of the Quality Assurance Unit  in Egyptian atomic energy Authority.
• Member in the Quality assurance unit in Faculty of Pharmacy, Delta University for Science and Technology.
• Member in Postgraduate and research committee in Faculty of Pharmacy, Delta   University for Science and Technology.
• Member of the Graduate Studies and Research Ethics Committee - College of Pharmacy - Delta University for Science and Technology.
• Oral examiner in many governmental and non-governmental universities.
• Supervisor of many graduation projects at the department.
• Supervising graduation projects for bachelor students at the Faculty of Pharmacy, Al-Bayan University - Iraq
• Member of the Scientific Committee - College of Pharmacy, Al-Bayan University - Iraq.
• Member of the Disciplinary and Ethical Committee - College of Pharmacy, Al- Bayan University - Iraq.
• Member of the Board of the Department of Pharmaceutics, College of Pharmacy Al-Bayan University, Iraq.
• Participation in many seminars organized by the College of Pharmacy, Al-Bayan  University, Iraq.

Workshops:
• 2017    Thirteen Arab conferences on peaceful uses of Atomic Energy. Hammatt Tunisia
• 2013 Attendance and participation in The Regional FRA Training course on Advanced Radiopharmacy Practices, Vienna.
• 2013 Attendance and participation in the First African Symposium on  Radiopharmacy services in Africa, Addis Ababa, Ethiopia.
• 2010 Quality control support for radio pharmaceutics Khartoum, Sudan

Publications

• Jawaher Abdullah Alamoud, Thanaa A. El-Masry  , Mohamed Nasr  Ismail T. Ibrahim  Hanaa A. Ibrahim 2 , Hebatallah M. Saad , Maysa M. F. El-Nagar * , Samar Zuhair Alshawwa 1 , Amal Alrashidi 1 and Enas I. El Zahaby. Fabrication of Nanocrystals for Enhanced Distribution of a Fatty Acid Synthase Inhibitor (Orlistat) as a Promising Method to Relieve Solid Ehrlich Carcinoma-Induced Hepatic Damage in Mice. Pharmaceuticals.
• M Dawoud, KM Attallah, IT Ibrahim, HM Karam… MitoQ and its hyaluronic acid–based nanopreparation mitigating gamma radiation–induced intestinal injury in mice: alleviation of oxidative stress and apoptosis. - Naunyn-Schmiedeberg's Archives of Pharmacology, 2024
• Basem Mansour, Yomna A. Salem, Khaled M. Attallah, O. A. El-kawy, Ismail T. Ibrahim, and Naglaa I. Abdel-Aziz Cyanopyridinone- and Cyanopyridine-Based Cancer Cell Pim-1 Inhibitors: Design, Synthesis, Radiolabeling, Biodistribution, and Molecular Modeling Simulation. ACS Omega 2023 8 (22), 19351-19366  DOI: 10.1021/acsomega.2c08304
• Motaleb, M. & Ibrahim, Ismail & Shweeta, H. & El-Halem, S.. (2024). Radiosynthesis of 99MTc-Montelukast as a Novel Potential Radiopharmaceutical Model for Lung Scanning. Pharmaceutical Chemistry Journal. 58. 10.1007/s11094-024-03179-x.
• Hend Fayez, Baher Daihom, Yasser Abd El-Aleem, I.T. Ibrahim, M.A. Motaleb,Brain nanotargeted [131I] I-Rolapitant as a model for brain imaging: Intranasal formulation, radiolabelling, biodistribution, and comparative study, Journal of Drug Delivery Science and Technology, Volume 86,2023,104705, ISSN 1773-2247,https://doi.org/10.1016/j.jddst.2023.104705.
• Motaleb, M.A., Attalah, K.M., Shweeta, H.A. and Ibrahim, IT.. Synthesis and biological evaluation of [131I]iodocarvedilol as a potential radiopharmaceutical for heart imaging. BMC Chemistry 17, 21 (2023).
• Basem Mansour, Yomna A. Salem, Khaled M. Attallah, O. A. El-kawy, Ismail T. Ibrahim, and Naglaa I. Abdel-ziz. Cyanopyridinone- and Cyanopyridine-Based Cancer Cell Pim-1 Inhibitors: Design, Synthesis, Radiolabeling, Biodistribution, and Molecular Modeling Simulation. ACS Omega 2023 8(22),19351-19366
• Mohamed Fawzi Kabil, Maha Nasr, Ismail T. Ibrahim, Yasser A. Hassan, Ibrahim M. El-Sherbiny, New repurposed rolapitant in nanovesicular systems for lung cancer treatment: Development, in- vitro assessment and in-vivo biodistribution study, European Journal of Pharmaceutical Sciences, 2022, 106119, ISSN 0928-0987,
• Sanad, MH, Gomaa, NM, El Bakary, NM, Ibrahim, IT, Massoud, A. Radioiodination of balsalazide, bioevaluation, and characterization as a highly selective radiotracer for imaging of ulcerative colitis in mice. J Label Compd Radiopharm. 2022; 1- 12. doi:10.1002/jlcr.3961 .
• Marwa Eid Sayyed, Mohamed Abd El-Motaleb, Ismail Taha Ibrahim, Hassan Medhat Rashed, Mohamed Ahmed El-Nabarawi, Mohamed Abdallah Ahmed, Preparation, characterization, and in vivo biodistribution study of intranasal 131I-clonazepam-loaded phospholipid magnesome as a promising brain delivery system, European Journal of Pharmaceutical Sciences,Volume 169,2022,106089, ISSN 0928-0987,
• Khalaf, H. , Jasim, R. and Ibrahim, I. (2021) Verbascoside—A Review of Its Antitumor Activities. Pharmacology & Pharmacy, 12, 109-126. doi: 10.4236/pp.2021.126011
• Ameer H. Alwash*, Baraa G. Alani, Ismail T. Ibrahim, RECENT PROGRESS IN DEVELOPING SELECTIVE HISTONE DEACETYLASE 6 INHIBITORS AS POTENTIAL EFFECTIVE ANTICANCER AGENTS: REVIEW. Kerbala journal of pharmacy and pharmaceutical science 24/04/2021
• Alani, B. , Alwash, A. and Ibrahim, I. (2020) Wide Applications of Chloroquine Other Than Antimalarial. Pharmacology & Pharmacy, 11, 251-281. doi: 10.4236/pp.2020.1110022.
• Walaa I. El-Ghareb, Mohamed M. Swidan, Ismail T. Ibrahim, Ahmed Abd El-Bary, Mina Ibrahim Tadros, Tamer M. Sakr, 99mTc-doxorubicin-loaded gallic acid-gold nanoparticles (99mTc- DOX-loaded GA-Au NPs) as a multifunctional theranostic agent, International Journal of Pharmaceutics, Volume 586,2020, 119514, ISSN 0378-5173,
• Talaat H. M.I. Aydia, I.T. Ibrahim, H. El-Said, K.M. El-Azony Documentation Center (NIDOC).Preparation of 186Re-Cefixime as a Potential Diagnostic and Therapeutic Agent for Bacterial Infection. Egypt. J. Rad. Sci. Applic., Vol. 32, No.1, pp. 95 - 103 (2019)
• Ibrahim I. T., Talaat H. M., Ayad R. A., and Farah K. Preclinical Evaluation of Radioiodinated Quinoxaline Derivative as a Possible Brain Imaging Agent. ISSN 1066-3622, Radiochemistry, 2018, Vol. 60, No. 6, pp. 638–643.
• Sayed M. E., Motaleb M. A., Ibrahim I. T., Awad G. A. S and R. O. Ahmed Intranasal drug delivery of iodohaloperidol as a radiopharmaceutical brain imaging agent Journal of Radioanalytical and Nuclear Chemistry.https://doi.org/10.1007/s10967-018-6359-2.
• Talaat H.M., Aydia M.I., Ibrahim I.T., El-Said H., K.M. El-Azony. Preparation of 186Re-Cefxime as a Potential Diagnostic and Therapeutic Agent for Bacterial Infection. Egypt. J. Rad. Sci.Applic., Vol. 32, No.1, pp. 95 – 103.
• Tamer M. Sakr, I. T. Ibrahim• Walaa H. Abd-Alla Molecular modeling and preclinical evaluation of radioiodinated tenoxicam for inflammatory disease diagnosis. journal of Radioanalytical and Nuclear Chemistry. https://doi.org/10.1007/s10967-018-5770-z
• Ahmed M. Elbarbary1, I. A. Ibrahim, H. M. Shafik2, Sameh H. Othman. Magnetic 99mTc- Core-Shell of Polyethylene Glycol/ Polyhydroxyethyl Methacrylate based on Fe3O4 Nanoparticles: Radiation Synthesis, Characterization and Biodistribution Study in Tumor Bearing Mice. Accepted in J. Advanced powederTechenology.
• El-Marakby EM, Hathout RM, Taha I, Mansour S, Mortada ND. A novel serum-stable liver targeted cytotoxic system using valerate-conjugated chitosan nanoparticles surface decorated with glycyrrhizin. Int J Pharm. 2017 Jun 15;525(1):123-138. doi: 10.1016/j.ijpharm.2017.03.081. Epub 2017 Apr 7. PMID: 28392279.
• Motaleb MA, Ibrahem IT, Ayoub VR, Geneidi AS. Preparation and biological evaluation of (99m)Tc-ropinirole as a novel radiopharmaceutical for brain imaging. J Labelled Comp Radiopharm. 2016 Apr;59(4):147-52. doi: 10.1002/jlcr.3380. Epub 2016 Feb 23. PMID: 26913705.
• Fahad M Al-Mutairi, Mohamed M Abdel-Daim, Ismaail T. Ibrahim, Salem A. Habib, and Heba M. Waly. The Potent Effect of a Newly Synthesized N-Butylpyridoquinoxaline 1,4-dioxide (NBPQD) Derivative as Antitumor agent in solid tumor model. International Journal of Pharmaceutical research &Allied Sciences, 2016, (2016) 5(1):203 – 218.
• I.T.Ibrahim, M.T.El-Kolaly , M.H.Aboumanei, A.A bdelbary. 125I labelling of clomiphene and biodistributions Studies for possible use as a model in breast cancer imaging. Applied RadiationandIsotopes115(2016)37–44.
• Ramy Said-Elbahr, Maha Nasr, Mohamed A. Alhnan , Ismail Taha , Omaima Sammour. Nebulizable colloidal nanoparticles co- encapsulating a COX-2 inhibitor and a herbal compound for treatment of lung cancer. European Journal of Pharmaceutics and Biopharmaceutics 103 (2016) 1–12
• Motaleb, M. A., Ibrahim, I. T., Abo Rizq, R. S. and Elzanfaly, E. S.. "Preparation, chromatographic evaluation and biodistribution of 99mTc-procainamide as a radiopharmaceutical for heart imaging" Radiochimica Acta, vol. 105, no. 3, 2017, pp. 215-223. https://doi.org/10.1515/ract-2015-2558
• Sameh H. Othmana,, I.T. Ibrahim, M.H. Hatab, Ahmed M. Elbarbary. Preparation, characterization and biodistribution in quails of99mTc-folic acid/chitosan nanostructure. International Journal of Biological Macromolecules 92 (2016) 550–560
• El-Motaleb Abd El-Rhman, Mohamed Abd, Ibrahim, Ismail Taha, Abd El-Halim, Sayed Mohamed and El-Tawoosy, Mahmoud El-Sayed. "Oxidative radioiodination of meclofenoxate as a preclinical brain imaging agent" Radiochimica Acta, vol. 104, no. 7, 2016, pp. 491-497. https://doi.org/10.1515/ract-2015-2557.
• Radioiodination of 2,3-dimethyl-4H-furo[3,2-c]coumarin and biological evaluation in solid tumor bearing mice S.M. Abd Elhalim, I.T. Ibrahim Volume 95, January 2015, Pages 153–158.
• M.A. Motaleb,, A. S. Farrag, I.T. Ibrahim, M.O. Sarhan, M. F. Ismail. preparation and molecular modeling of radioiodo- proprabolol as a novel potential radiopharmaceutical for lung perfusion scan. International Journal of Pharmacy and Pharmaceutical Sciences.ISSN- 0975-1491 Vol 7, Issue 8, 2015
• M.A. Motaleb, I.T. Ibrahim, J. M. Rashed . A. A. Elbary. Preparation of radioiodinated ritodrine as a potential agent for lung imaging J Radioanal Nucl Chem (2014) 300:1227–1233 DOI10.1007/s10967-014-3077-2.
• Salem A. Habib, Ismail T. Ibrahim, Mohamed A. Abd- Eldaye, Mamdouh M. El-Sheshtawey, Heba M. Waly. Radioiodination and biodistribution of NBNPQD (2-benzyl-1-oxo-1,2-dihydropyrido[4,3-b]quinoxaline 5,10-dioxide) in tumor bearing mice. Natural Science, Vol.4 No.12, 2012
• El-Tawoosy. M and Ibrahim. I. T. Radioiodination and Biological Evaluation of Salbutamol as a β2-Adrenoceptor Agonist. Radiochemistry, 2012, Vol. 54, No. 4, pp. 401–406.
• I. T. Ibrahim, M. El-Tawoosy, and H. M. Talaat. Labeling of Tannic Acid with Technetium-99m for Diagnosis of Stomach Ulcer. nternational Scholarly Research Network ISRN Pharmaceutics Volume 2011, Article ID 578570, 6 pages doi:10.5402/2011/578570
• I.T. Ibrahim, M. El-Tawoosy. And M. A. Wally. Synthesis, Labeling, and Biological Evaluation of 2-{[Benzyl(cyanomethyl)amino]methyl}-3-(ethoxycarbonyl)- quinoxaline 1,4-Dioxide in Ascites Bearing Mice
• Maha Nasr 1, Gehanne A.S. Awad, Samar Mansour 1, Abdelhamid Al Shamy ,Ismail Taha , Nahed D. Mortada Different Modalities of NaCl Osmogen in Biodegradable Microspheres for Bone
• Deposition of Risedronate Sodium by Alveolar Targeting. European Journal of Pharmaceutics and Biopharmaceutics (2011).
• I. T. Ibrahim, K. M.Attallah, M.T. El-Kolaly, Samy A. Abedelazim. Effect of Levamisole on the Biological Activity of Labeled Iodo-deoxyuridine in EAC Bearing Mice. IJNESE Vol.1 No. 1( 2011) PP.15-21.
• M. E. Moustapha, M. A. Motaleb & I. T. Ibrahim. Synthesis of
• 99mTc-oxybutynin for M3-receptor-mediated imaging of urinary bladder. J Radioanal Nucl Chem.287 (2011) 35-40.
• A. M. Amin, K. M. El-Azony, I. T. Ibrahim: Application of 99Mo/99mTc alumina generator in the labeling of metoprolol for diagnostic purposes J. Labell. Compds. Radiopharm.Volume 52 Issue 11, Pages 467 – 472.
• I.T.Ibrahim, A.M.Amin, and K.M.El-Azony :Preparation of Radioiodo-Metoprolol and Its Biological Evaluation as a Possible Cardiac Imaging Agent Radiochemistry.
• Samh R. El Gogary. Mohamed A. Waly. Ismail T. Ibrahim and Osama Z. El- Sepelgy. (2010). Synthesis and UV absorption of new conjugated quinoxaline 1,4-dioxide derivatives anticipated as tumor imaging and cytotoxic agents. Monatsh Chem. 141;1253-1262.
• I.T. Ibrahim, M. A. Motaleb and K.M. Attallah Synthesis and Biological Distribution of 99mTc-Norfloxacin complex , a novel agent for detecting sites of infection. . J Radioanal Nucl Chem.285(2010) 431-436.
• I.T. Ibrahim. Labeling and Biodistribution of Methotrexate in
• EAC Tumor Bearing Mice. Arab. J. Nucl. Sci Appl.43(4)19- 31.2010.
• H. A. Salem, E. Noaman, I. T. Ibrahim M. T. El-Kolalyand H. A. El-Kashef: Influence of Livamisole to Radiotherapeutic Activity of 125-I-Vidarabine in EAC Mice. . Tenth Arab. Conference. Pace Uses of Atomic Energy. Arbil Iraq. 12-16-Dec. 2010.
• I. T. Ibrahim , M. A. Wally, Synthesis, Labeling and Biodistribution of 99mTc-3- amino-2-quinoxalin-carbonitrile 1,4- dioxide in Tumor Bearing. J Radioanal Nucl Chem.285(2010) 169-175.
• I.T. Ibrahim and K.M. Attallah Preparation of 99mTc-Ancitabine as
• a Possible Tumor Imaging Agent. Arab. J. Nucl. Sci Appl. 43(4)65- 71.
• H.A. Salem, E. Noaman, M.A. Motaleb, M.T. Kollaly and E. Taha (2010). Radioactive Iodo-Azathioprine as a Model for Cancer Imaging and Therapy. Arab J. Nucl. Sci. Appl. 43(1). 53-63.
• H. A. Salem, Eman Noaman, M. T. El-Kolaly, I. Taha and H. A. El-Kashef: Dexamethasone modulates the Radiotherapeutic Effect of Labeled Iodo-Ancitabine in Solid Tumor Bearing Mice. Arab J. Nucl. Sci. Appl. 43(1). 105-120
• I. T. Ibrahim. Labeling of metronidazole with techentiom-99m as a model for tumor imaging. Journal of radioanalytical and Nuclear application (2009). 281; 669-674.
• H.M. Talaat. I.T. Ibrahim and K.M. Attallah. Comparative Study Between 99mTc-Kanamycin and 99mTc- Gentamycin as Diagnostic Agents for Bacterial Infection. Isotope, Rad. Res., 41;2(2009)557-568
• Noaman E., Salem HA., Motaleb MA., Taha E., Kollaly MT. (2007): Treatment and imaging of cancer using radiolabeled iodo- vidarabine. Arab J. Nucl. Sci. Appl. 37(1). 1-13.

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